The levers should be at full power. At least that is how the lights are designed to work with our remote system, and I assume the PW's are designed the same way. However, Pocket Wizard would be able to tell you for sure.
As for using a manual flash and a TTL flash simultaneously, they will sync together and it can work in some circumstances. However, it is not typically advisable unless you really know what you are doing.
The reason for this is the camera sends a known amount of light from the speed light just before the exposure. The camera calculates the exposure from this known amount and tells the speedlite how much energy it needs to create a proper exposure. This typically works OK, except you then add the light from the White Lightning. So you have good exposure, then add more light, you end up with over exposure.
Additionally, in a portrait type setting, manual flash is often preferred, as it is more consistent than TTL. Set manual flash, and it is that power every shot (assuming the light is allowed to recycle). TTL can change exposure from shot to shot based on minor changes even in composition.
If you have a manual flash exposing a large room (reception hall, for example) and a speedlight illuminating localized scenes (close up shots of guests), TTL can be mixed reasonably well with manual flash.
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